A systematic evaluation of the cellular innate immune response during the process of human atherosclerosis, paper supported by CarTarDis published by AHA
The concept of innate immunity is well recognized within the spectrum of atherosclerosis, which is primarily dictated by macrophages. Although current insights to this process are largely based on murine models, there are fundamental differences in the atherosclerotic microenvironment and associated inflammatory response relative to humans. In this light, Cartardis partner, LUMC characterized the cellular aspects of innate immune response in normal, nonprogressive, and progressive human atherosclerotic plaques. This research was partly CarTarDis, FP7 HEALTH.2013.2.4.2-1).
The paper ‘A systematic evaluation of the cellular innate immune response during the process of human atherosclerosis’, by R.A. van Dijk, MD; J.F. Hamming, MD PhD; F.D. Kolodgie, PhD; R. Virmani MD; A.F. Schaapherder MD, PhD; J.H. Lindeman MD, PhD, can be assessed via:
This interesting work was also presented as a poster at the conference Frontiers in CardioVascular Biology, July 2016, Florence, Italy